Pharmacy MCQ Questions - Set 14.
B. Energy requirement for σ − σ* is in the range of 120-200nm.
C. It is volatile.
D. It is immiscible with water.
2. Quaternary structure in protein molecules refers to the.
A. Arrangement of multiple domains in a single polypeptide chain.
B. Specific arrangement of multiple subunits in multi-subunit proteins.
C. Formation of molten globules.
D. Protein folding in single subunit proteins.
3. Interleukins are.
A. Polypeptide cytokines important in the inflammatory cascade.
B. Prostaglandins that account for gastrointestinal disorders.
C. Enkephalins which are specific for asthma.
D. Dipeptides which have antimicrobial properties.
4. Phase I clinical studies of a drug under development is generally carried out on.
A. At least 10,000 people from different ethnic communities and a wide range of age groups.
B. A medium sized group of 500-1000 patients suffering from the disease for which the drug is being developed.
C. A small group of 20-100 healthy male and female volunteers.
D. Reliable in-intro cell-lines derived from people suffering from the disease.
5. A young patient complains that he gets severe shortness of breath whenever he takes aspirin for a headache. Increased levels of a substance responsible for aspirin hypersensitivity is.
A. Prednisone.
B. Prostacycline.
C. Ibuprofen.
D. Leukotriene LTC4.
6. Effects seen only with depolarizing blockade include all of the following Except.
A. Hypercaliemia.
B. A decrease in intraocular pressure.
C. Emesis.
D. Muscle pain.
7. Correct statements about cortisol (hydrocortisone. include all of the following, Except.
A. Cortisol is synthesized from cholesterol.
B. ACTH governs cortisol secretion.
C. Most cortisol is inactivated in the liver.
D. The half-life of cortisol in the circulations is normally about 60-90 hours.
8. Which neuromuscular blocking agent is contraindicated in patients with glaucoma?
A. Tubocurarine.
B. Succinylcholine.
C. Pancuronium.
D. Gallamine.
9. Which of the following glucocorticoids is a short- to the medium-acting drug?
A. Prednisolone.
B. Dexamethasone.
C. Triamcinolone.
D. All of the above.
10. Which of the following diseases can augment the neuromuscular blockade produced by nondepolarizing muscle-relaxants?
A. Myasthenia gravis.
B. Burns.
C. Asthma.
D. Parkinsonism.
11. the drug which belongs to nucleoside reverse transcriptase inhibitors.
A. Didanosine.
B. Gancyclovir.
C. Nevirapine.
D. Vidarabine.
12. The unwanted effects of zidovudine.
A. Hallucinations, dizziness.
B. Anemia, neutropenia, nausea, insomnia.
C. Hypertension, vomiting.
D. Peripheral neuropathy.
13. Indicate the agent, which effectively antagonizes the neuromuscular blockade caused by nondepolarizing drugs.
A. Atropine.
B. Neostigmine.
C. Acetylcholine.
D. Pralidoxime.
14. Which of the following sympathomimetics acts indirectly?
A. Epinephrine.
B. Norepinephrine.
C. Ephedrine.
D. Methoxamine.
15. Which of the following statements is not correct?
A. ALFA receptors increase arterial resistance, while β-receptor promote smooth muscle relaxation.
B. The skin and splanchic vessels have predominantly alfa receptors.
C. Vessels in a skeletal muscle may constrict or dilate depending on whether alfa or beta receptors are activated.
D. Skeletal muscle vessels have predominantly alfa receptors and constrict in the presence of epinephrine and norepinephrine.
Answers
1. Energy requirement for σ − σ* is in the range of 120-200nm.2. Specific arrangement of multiple subunits in multi-subunit proteins.
3. Polypeptide cytokines important in the inflammatory cascade.
4. A small group of 20-100 healthy male and female volunteers.
5. Prostacycline.
6. A decrease in intraocular pressure.
7. The half-life of cortisol in the circulations is normally about 60-90 hours.
8. Succinylcholine.
9. Prednisolone.
10. Myasthenia gravis.
11. Didanosine.
12. Anemia, neutropenia, nausea, insomnia.
13. Neostigmine.
14. Ephedrine.
15. Skeletal muscle vessels have predominantly alfa receptors and constrict in the presence of epinephrine and norepinephrine.
