Pharmacy MCQ Questions - Set 11.
1. Barbiturates with substitution at the following position possess acceptable hypnotic activity.
A. 1, 3-Disubstitution.
B. 5, 5-Disubstitution.
C. 1, 5-Disubstitution.
D. 3, 3-Disubstitution.
2. Selective serotonin reuptake inhibitor is.
A. Imipramine.
B. Iproniazide.
C. Fluoxetin.
D. Naphazoline.
3. Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system.
A. Pyrimidine.
B. Benzimidazole.
C. Benzothiazole.
D. Oxindole.
4. A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is.
A. Fluvastatin.
B. Cerivastatin.
C. Lovastatin.
D. Somatostatin.
5. Cyclophosphamide as anticancer agent acts as.
A. Alkylating agent before metabolism.
B. Alkylating agent after metabolism.
C. Phosphorylating agent after metabolism.
D. DNA intercalating agent.
6. Artemisinin contains the following group in its structure.
A. An endoperoxide.
B. An exoperoxide.
C. An epoxide.
D. An acid hydrazide.
7. Indicate the HPLC detector that is most sensitive to change in temperature.
A. PDA detector.
B. Refractive Index detector.
C. Electrochemical detector.
D. Fluorescence detector.
8. One of the following statements is NOT true.
A. Accuracy expresses the correctness of measurement.
B. Precision represents reproducibility of measurement.
C. High degree of precision implies high degree of accuracy also.
D. High degree of accuracy implies high degree of precision also.
9. In thiazides following substituent is essential for diuretic activity.
A. Chloro group at position 6.
B. Methyl group at position 2.
C. Sulphamoyl group at position 7.
D. Hydrophobic group at position 3.
10. Streptomycin can NOT be given orally for treatment of tuberculosis because.
A. It gets degraded in the GIT.
B. It causes severe diarrhoea.
C. It causes metallic taste in the mouth.
D. it is not absorbed from the GIT.
11. In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than.
A. 350 nm.
B. 200 nm.
C. 300 nm.
D. 250 nm.
12. Glass transition temperature is detected through.
A. X-Ray diffractometery.
B. Solution calorimetery.
C. Differential scanning calorimeter.
D. Thermogravimetric analysis.
13. In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their.
A. Volatility.
B. Solubility.
C. Thermal conductivity.
D. Polarizability.
14. Oxidative phosphorylation involves.
A. Electron transport system.
B. Substrate level phosphorylation.
C. Reaction catalyzed by succinic thiokinase in TCA cycle.
D. None of the above.
15. Coulter counter is use the in determination of.
A. Particle surface area.
B. Particle size.
C. Particle volume.
D. All of A, B, C.
2. Fluoxetin.
3. Benzimidazole.
4. Lovastatin.
5. Alkylating agent after metabolism.
6. An endoperoxide.
7. Refractive Index detector.
8. High degree of precision implies high degree of accuracy also.
9. Sulphamoyl group at position 7.
10. It is not absorbed from the GIT.
11. 350 nm.
12. Differential scanning calorimeter.
13. Polarizability.
14. Electron transport system.
15. All of A, B, C.
A. 1, 3-Disubstitution.
B. 5, 5-Disubstitution.
C. 1, 5-Disubstitution.
D. 3, 3-Disubstitution.
2. Selective serotonin reuptake inhibitor is.
A. Imipramine.
B. Iproniazide.
C. Fluoxetin.
D. Naphazoline.
3. Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system.
A. Pyrimidine.
B. Benzimidazole.
C. Benzothiazole.
D. Oxindole.
4. A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is.
A. Fluvastatin.
B. Cerivastatin.
C. Lovastatin.
D. Somatostatin.
5. Cyclophosphamide as anticancer agent acts as.
A. Alkylating agent before metabolism.
B. Alkylating agent after metabolism.
C. Phosphorylating agent after metabolism.
D. DNA intercalating agent.
6. Artemisinin contains the following group in its structure.
A. An endoperoxide.
B. An exoperoxide.
C. An epoxide.
D. An acid hydrazide.
7. Indicate the HPLC detector that is most sensitive to change in temperature.
A. PDA detector.
B. Refractive Index detector.
C. Electrochemical detector.
D. Fluorescence detector.
8. One of the following statements is NOT true.
A. Accuracy expresses the correctness of measurement.
B. Precision represents reproducibility of measurement.
C. High degree of precision implies high degree of accuracy also.
D. High degree of accuracy implies high degree of precision also.
9. In thiazides following substituent is essential for diuretic activity.
A. Chloro group at position 6.
B. Methyl group at position 2.
C. Sulphamoyl group at position 7.
D. Hydrophobic group at position 3.
10. Streptomycin can NOT be given orally for treatment of tuberculosis because.
A. It gets degraded in the GIT.
B. It causes severe diarrhoea.
C. It causes metallic taste in the mouth.
D. it is not absorbed from the GIT.
11. In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than.
A. 350 nm.
B. 200 nm.
C. 300 nm.
D. 250 nm.
12. Glass transition temperature is detected through.
A. X-Ray diffractometery.
B. Solution calorimetery.
C. Differential scanning calorimeter.
D. Thermogravimetric analysis.
13. In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their.
A. Volatility.
B. Solubility.
C. Thermal conductivity.
D. Polarizability.
14. Oxidative phosphorylation involves.
A. Electron transport system.
B. Substrate level phosphorylation.
C. Reaction catalyzed by succinic thiokinase in TCA cycle.
D. None of the above.
15. Coulter counter is use the in determination of.
A. Particle surface area.
B. Particle size.
C. Particle volume.
D. All of A, B, C.
Answers
1. 5, 5-Disubstitution.2. Fluoxetin.
3. Benzimidazole.
4. Lovastatin.
5. Alkylating agent after metabolism.
6. An endoperoxide.
7. Refractive Index detector.
8. High degree of precision implies high degree of accuracy also.
9. Sulphamoyl group at position 7.
10. It is not absorbed from the GIT.
11. 350 nm.
12. Differential scanning calorimeter.
13. Polarizability.
14. Electron transport system.
15. All of A, B, C.
