Pharmacy MCQ Questions - Set 12.
B. Tri-exponentially.
C. Non-exponentially.
D. Mono-exponentially.
2. The temperature condition for storage of drug products under cold temperature is given as.
A. Temperature between 8°C and 25°C.
B. Temperature below 20C.
C. Temperature at 0°C.
D. Temperature between 2°C and 8°C.
3. Many xenobiotics are oxidized by cytochrome P450 in order to.
A. Increase their biological activity.
B. Increase their disposition in lipophilic compartments of the body.
C. Increase their aqueous solubility.
D. All of the above.
4. The following protein/polypeptide has a quaternary structure.
A. cc-Chymotrypsin.
B. Hemoglobin.
C. Insulin.
D Myoglobin.
5. In nail polish, following polymer is used as a film-former.
A. Nitrocellulose.
B. Polylactic acid.
C. Hydroxypropyl methylcellulose.
D. Cellulose acetate phthalate.
6. Rabies vaccine (living) is prepared using.
A. Sheep blood.
B. Mice lymph.
C. Horse plasma.
D. Fertile eggs.
7. A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is.
A. 125%.
B. 250 %.
C. 12.5%.
D. 1.25%.
8. Geriatric population should be included in the following Phase of clinical trials.
A. Phase I.
B. Phase II.
C. Phase III.
D. Phase IV.
9. Class 100 area is referred to.
A. Manufacturing area.
B. Aseptic area.
C. Clean room.
D. Warehouse.
10. How many mL of a 1:500 w/v stock solution should be used to make 5 litres of 1:2000 w/v solution?
A. 750 ml.
B. 1000 ml.
C. 1250 ml.
D. 1500 ml.
11. The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be.
A. 10 L.
B. 100 L.
C. 1.0 L.
D. 0.10 L.
12. It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half-life of 1.386 hours and Vd of 5 L. The dose required in a sustained release product will be.
A. 600 mg.
B. 300 mg.
C. 30 mg.
D. 60 mg.
13. TGA is the regulatory authority of the country.
A. USA.
B. India.
C. Australia.
D. Europe.
14. Drugs in suspensions and semi-solid formulations always degrade by.
A. First order kinetics.
B. Second order kinetics.
C. Zero-order kinetics.
D. Non-linear kinetics.
15. In which of the following techniques the sample is kept below triple point?
A. Lyophilization.
B. Spray drying.
C. Spray congealing.
D. Centrifugation.
Answers
1. Mono-exponentially.2. Temperature between 2°C and 8°C.
3. All of the above.
4. Hemoglobin.
5. Nitrocellulose.
6. Fertile eggs.
7. 12.5%.
8. Phase II.
9. Aseptic area.
10. 1250 mL.
11. 10 L.
12. 300 mg.
13. Australia.
14. Zero-order kinetics.
15. Lyophilization.
